North America (U.S., Canada and Mexico) is at a crossroad of economic development. The U.S. and Canada are transitioning from the Post-Industrial to the Information Age. Mexico, an upper-middle –economy, is on the verge of becoming a developed country, despite its present difficulties. All three countries are linked geographically, economically, politically and culturally. Although N.A.F.T.A has not received much attention lately, this does not obviate joint development opportunities. Infrastructure coordination, such as high-speed rail (HSR), can strengthen all three countries and create additional opportunities. It could be the impetus for a new era of sustainable prosperity for all three countries….